Polysorbate and Solubilizer

Solubilizer SL-11, occurring as a transparent liquid, can be used to prepare nano-emulsions of various hydrophobic drugs (the particle sizes are below 50 nm). Since this possesses excellent self-emulsifying properties, this is the most appropriate agent for SEDDS (Self Emulsifying Drug Delivery Systems). Following oral administration, this solubilizer SL-11 augments intestinal absorption of drugs.Once the hydrophobic drug is dissolved in SL-11 as directed in the attached protocol, SEDDS reagents containing the drug can be easily prepared. NOF has also capability of the toll development by using this technology.

Cutting-Edge Technology for Self-emulsifying Agents
(Particle size: < 50nm)

• Easy preparation
• Applicable to various kinds of hydrophobic drugs
• Applicable to soft capsules for oral use
• Most suitable for SEDDS agent
• Improvement of intestinal absorption following oral administration
• Toll development for formulations
• Comply with bulk supply requests