NOF CORPORATION

Polysorbate and Solubilizer

Welcome to our website on Polysorbate 80(HX2)TM

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Application

@Injection Formulation

Polysorbate 80(HX2)TM has outstanding quality compared with current injectable grade of Polysorbate 80. Polysorbate 80(HX2)TM gives the best result for Injection Formulation and will be a grobal standard for injectable grade.

  • Low Allergic Reaction
  • Increased Concentration Against Drug
  • Low Toxicity
  • Low Peroxide


@Improvement of Analysis

Because of its colorless characteristics, Polysorbate80(HX2)TM can be provided the best analytical performance than ever. There is less interference UV region at UV spectrum measurement. On the other hand, conventional Polysorbate 80 contains numerous impurities and different fatty acid residues. Due to this, there are some interferences of desired peak of drug at HPLC analysis. Ultra-pure Polysorbate 80TM enables to improve analytical performance at HPLC analysis.


@For Stable Formulation

Polysorbate 80 is frequently used for pharmaceutical formulations as an emulsifier, solubilizer and stabilizer. Improving its characteristics (color, odor, oxidation stability, cytotoxicity and hemolysis) by ultra-pure Polysorbate 80(HX2)TM is very suitable for pharmaceutical application. NOF has more stable and versatile formulation technology for pharmaceuticals, emulsification, and solubilization using our highpure oleic acid derivatives, including Polysorbate 80(HX2)TM, shown as a water/oil/water emulsion in below.

graph
W/O/W emulsion using ultra-pure Polysorbate 80(HX2)TM (Scale bar=5ƒÊm)